Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations
نویسندگان
چکیده
منابع مشابه
[Antiphospholipid antibody: laboratory, pathogenesis and clinical manifestations].
Antiphospholipid antibodies (aPL) represent a heterogeneous group of antibodies that recognize various antigenic targets including beta2 glycoprotein I (beta2GPI), prothrombin (PT), activated protein C, tissue plasminogen activator, plasmin and annexin A2. The most commonly used tests to detect aPL are: lupus anticoagulant (LAC), a functional coagulation assay, anticardiolipin antibody (aCL) an...
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Sir, I would like to correct my comment in my original letter,[1] commenting on the article published by Rishi et al.,[2] which is “ this condition is unlikely to occur on ground of embryology, as the central retinal artery develops from a single hyaloid artery and enters the lamina cribrosa.” Now, my attention has been drawn by Dr. S S Hayreh that on certain occasions it is possible to have tw...
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Antiphospholipid antibody syndrome is characterized by venous and/or arterial thrombosis and/or pregnancy morbidity associated with antiphospholipid antibodies (aPL), such as anticardiolipin antibodies, anti beta 2 glycoprotein I antibodies and positive lupus anticoagulant test. This syndrome may potentially affects any organ system including the skin. Livedo reticularis is the most frequently ...
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Diffuse systemic sclerosis (SSc) is a chronic disease of unknown cause characterized by diffuse fibrosis and vascular abnormalities in the skin and internal organs. Pathogenesis of SSc involves immunologic mechanisms, vascular damage and activation of fibroblasts. SSc varies in severity and progression; most patients eventually develop visceral complications, which are the usual causes of death...
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ژورنال
عنوان ژورنال: Reumatismo
سال: 2011
ISSN: 2240-2683,0048-7449
DOI: 10.4081/reumatismo.2010.65